OUR FOCUS

Renaissance Pharma is a global biopharmaceutical company intent on developing and commercialising novel paediatric oncology therapeutics to bring life-enhancing benefits to children across the world.

Neuroblastoma

Neuroblastoma is a paediatric cancer that arises from the abnormal development of cells of the sympathetic nervous system. The average age at diagnosis is 17 months1. Neuroblastomas account for close to 10% of all childhood cancers, yet cause 15% of childhood cancer deaths2. This discrepancy reflects the variation in biological and clinical presentations of this disease. Whilst 90% of patients with low-risk disease are cured, less than 50% of patients with high-risk neuroblastoma go on to survive2,3. There is a need for better treatment, particularly for high-risk children, where current treatments are highly intensive. This requires the development and commercialisation of improved therapeutics. Renaissance Pharma has recognised this need and, accordingly, Neuroblastoma represents our primary focus area.

References

1. Ries, L.A.G. ed., 1999. Cancer incidence and survival among children and adolescents: United States SEER program, 1975-1995 (No. 99). National Cancer Institute.

2. Whittle, S.B., Smith, V., Doherty, E., Zhao, S., McCarty, S. and Zage, P.E., 2017. Overview and recent advances in the treatment of neuroblastoma. Expert review of anticancer therapy, 17(4), pp.369-386.

3. Qiu, B. and Matthay, K.K., 2022. Advancing therapy for neuroblastoma. Nature Reviews Clinical Oncology, 19(8), pp.515-533.